Dr. Ziegler’s research on sympathetic nervous control of the cardiovascular system bridges basic and clinical research in over 300 publications. His recent studies have examined how adrenergic genetic polymorphisms alter control of blood pressure in man and transgenic mouse. His NASA research has examined why astronauts lose postural control of blood pressure on their return from space flight, for which he received aNASA award. Dr. Ziegler has chaired several NIH Review Committees. He is particularly interested in mechanisms that allow the brain to use the sympathetic nervous system to alter physiology.